Published in 1976, Interview with the Vampire quickly became a cult success, and a prominent influence on present Goth culture. The novel was set apart from its predecessors of the vampire genre by its confessional tone from the vampire's perspective, touching on existential despair and the sheer boredom of lifeless immortality. Rice reported in her biography that the themes of vampirism and the tone of the book echoed the loss of her daughter Michele from leukemia in 1972. Interview is distinct from its sequels in its sombre tone, and subsequently the perspective shifts to that of the vivacious Lestat. Nevertheless, it remains the best-selling and best-received of Rice's books.